Penicillanic acid dioxide prodrug

摘要: A compound of the formula ##STR1## is a prodrug 4,4-dioxopenicillanic acid, wherein R hydrogen or methyl; 1 , 2 and 3 (a) when taken individually are each alkyl containing one to four carbon atoms, (b) together with nitrogen which they attached form five- six-membered saturated monocyclic moiety, an eight-membered bicyclic moiety aromatic cyclic annulated zero, two fused benzene rings, proviso that any not part atoms; X - pharmaceutically-acceptable anion. The can be included beta-lactam antibiotic in pharmaceutical composition employed treatment infection mammals. above-described compounds hydrolyze vivo acid.