Biochemical systems analysis

作者: Michael A. Savageau

DOI: 10.1016/S0022-5193(70)80013-3

关键词:

摘要: At present there is no general solution for the dynamic equations describing an arbitrary system of enzyme-catalyzed reactions. The reasons are three-fold. First, available methods kinetic analysis inadequate obtaining complete rate law complex Second, even if were available, amount experimental data required such might be prohibitive. In addition, rate-equations represents enormous nonlinear problem. These difficulties have been largely circumvented by utilizing a suitable approximation procedure that based on nature and yet sufficiently simple to treat mathematically. this paper approximate developed in matrix form, program n chemical using conventional numerical described. Sample solutions also presented show resulting from simplifying retain capability many more interesting behavior patterns associated with biological systems.

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