作者: Clinton J. Dahlberg , Veera Konda , Anuradha Desai , Jan Urban , Brian J. Carroll
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摘要: The present application provides novel tetrahydro-isohumulone (THIAA) derivatives and substantially enantiomerically pure compositions pharmaceutical formulations thereof. further methods of using the disclosed compounds to activate PPARy, inhibit inflammation, treat conditions associated with inflammation responsive PPARy modulation such as diabetes.