Production of fucosylated glycoproteins

作者: Noora Salovuori , Heli Viskari , Jussi Joensuu , Merja Penttilä , Markku Saloheimo

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摘要: Described herein are compositions including filamentous fungal cells, such as Trichoderma having reduced protease activity and expressing fucosylation pathway. Further described methods for producing a glycoprotein fucosylated N-glycan, using genetically modified example, the expression system.