Bipolar disorder is a common mental disorder which is relapsing and remitting in nature. Subsyndromal symptoms are common and associated with poorer outcomes. Management of the disorder can be challenging and depends on the polarity and severity of the mood episode.

David J. Miklowitz, Michael W. Otto, Ellen Frank, Noreen A. Reilly-Harrington, Jane N. Kogan, Gary S. Sachs, Michael E. Thase, Joseph R. Calabrese, Lauren B. Marangell, Michael J. Ostacher, Jayendra Patel, Marshall R. Thomas, Mako Araga, Jodi M. Gonzalez, Stephen R. Wisniewski, Intensive psychosocial intervention enhances functioning in patients with bipolar depression: results from a 9-month randomized controlled trial. American Journal of Psychiatry. ,vol. 164, pp. 1340- 1347 ,(2007) , 10.1176/APPI.AJP.2007.07020311

Kate EA Saunders, Keith Hawton, Clinical assessment and crisis intervention for the suicidal bipolar disorder patient. Bipolar Disorders. ,vol. 15, pp. 575- 583 ,(2013) , 10.1111/BDI.12065

Danielle M Novick, Holly A Swartz, Ellen Frank, Suicide attempts in bipolar I and bipolar II disorder: a review and meta-analysis of the evidence Bipolar Disorders. ,vol. 12, pp. 1- 9 ,(2010) , 10.1111/J.1399-5618.2009.00786.X

Gianluca Rosso, Umberto Albert, Filippo Bogetto, Giuseppe Maina, Axis II comorbidity in euthymic bipolar disorder patients: no differences between bipolar I and II subtypes. Journal of Affective Disorders. ,vol. 115, pp. 257- 261 ,(2009) , 10.1016/J.JAD.2008.08.009

Margreet ten Have, Wilma Vollebergh, Rob Bijl, Willem A. Nolen, Bipolar disorder in the general population in The Netherlands (prevalence, consequences and care utilisation): results from The Netherlands Mental Health Survey and Incidence Study (NEMESIS). Journal of Affective Disorders. ,vol. 68, pp. 203- 213 ,(2002) , 10.1016/S0165-0327(00)00310-4

M Alda, LITHIUM IN THE TREATMENT OF BIPOLAR DISORDER: PHARMACOLOGY AND PHARMACOGENETICS Molecular Psychiatry. ,vol. 20, pp. 661- 670 ,(2015) , 10.1038/MP.2015.4

Helle K Schoeyen, Ute Kessler, Ole A Andreassen, Bjoern H Auestad, Per Bergsholm, Ulrik F Malt, Gunnar Morken, Ketil J Oedegaard, Arne Vaaler, None, Treatment-Resistant Bipolar Depression: A Randomized Controlled Trial of Electroconvulsive Therapy Versus Algorithm-Based Pharmacological Treatment American Journal of Psychiatry. ,vol. 172, pp. 41- 51 ,(2015) , 10.1176/APPI.AJP.2014.13111517

Urban Ösby, Lena Brandt, Nestor Correia, Anders Ekbom, Pär Sparén, Excess Mortality in Bipolar and Unipolar Disorder in Sweden Archives of General Psychiatry. ,vol. 58, pp. 844- 850 ,(2001) , 10.1001/ARCHPSYC.58.9.844

T. Kendall, R. Morriss, E. Mayo-Wilson, E. Marcus, , Assessment and management of bipolar disorder: summary of updated NICE guidance. BMJ. ,vol. 349, pp. 5673- ,(2014) , 10.1136/BMJ.G5673

Konstantinos N Fountoulakis, Dimitrios Kontis, Xenia Gonda, Lakshmi N Yatham, A systematic review of the evidence on the treatment of rapid cycling bipolar disorder. Bipolar Disorders. ,vol. 15, pp. 115- 137 ,(2013) , 10.1111/BDI.12045