Progressive Resistance Training for Improving Health-Related Outcomes in People at Risk of Fracture: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

摘要: OBJECTIVE Osteoporosis clinical practice guidelines recommend exercise to prevent fractures, but the efficacy of depends on types, population studied, or outcomes interest. The purpose this systematic review was assess effects progressive resistance training (PRT) health-related in people at risk fracture. METHODS Multiple databases were searched October 2019. Eligible articles randomized controlled trials PRT interventions men and women ≥50 years with low bone mineral density (BMD) fracture history. Descriptive information mean difference (MD) SD directly extracted for included trials. A total 53 studies included. RESULTS number falls (incidence rate ratio [IRR] = 1.05; 95% CI 0.91 - 1.21; 7 studies) falling (risk [RR] 1.23; 1.00 1.51; 5 are uncertain. improved performance Timed "Up Go" test (MD = -0.89 seconds; CI = -1.01 -0.78; 13 quality life (standardized MD = 0.32; CI = 0.22-0.42; 20 studies). may increase femoral neck (MD = 0.02 g/cm2; CI = 0.01-0.03; 521 participants, not lumbar spine BMD CI = -0.01-0.05; 4 studies), whereas hip uncertain (MD = 0.00 g/cm2; CI = 0.00-0.01; 435 reduced pain MD = -0.26; CI = -0.37 -0.16; 17 Sensitivity analyses, including PRT-only studies, confirmed these findings. CONCLUSION Individuals fractures should be encouraged perform PRT, as it improve BMD, life, physical functioning. also pain; however, whether increases decreases falls, experiencing a fall, fall-related injuries is IMPACT have positive functioning, pain, adverse events rare. LAY SUMMARY Exercise recommended osteoporotic fractures. Our study showed that improves reduces pain. unclear. Adverse rare, often minor (eg, soreness, musculoskeletal injury). Considering benefits safety, engage interventions.