Virus-related pathology: is the continued presence of the virus necessary?

摘要: Publisher Summary This chapter examines the effect of viruses in inducing modifications chromosomes, immune system interactions, and cell metabolism to support such a hypothesis that virus may no longer be present when pathology appears. When vaccines were available protect population against major epidemics, then chronic, recurrent, or persistent infections came into focus. Viruses are everywhere all organisms permanently exposed them. The result this contact depends on particular moment t which given is virus. Rubella, for example, provokes very benign disease adults, but can induce abnormalities differentiating fetus. Although interferon active aggression, excess has toxic block differentiation. capacity several act as cellular mutagens by modifying chromosomes well established, whatever molecular mechanism be. Mutations at level carefully analyzed their tumorigenic potential.