Risk Stratification for Thromboprophylaxis in Atrial Fibrillation

摘要: Atrial Fibrillation (AF) is an independent risk factor for stroke [1] with approximately sixfold increase in the stroke. Patients AF association valvular heart disease are at particularly high (17 fold) and all such patients should be anticoagulated absence of contraindications. Nevertheless, non-valvular not uniform. For example, rate varies from 0.5% per annum amongst young lone [2] to 12% previous history or transient ischemic attack [3]. This age differential important as frequency dramatically increases age, so that more than one third strokes over 75 years attributable [4]. a small but significant proportion cardiogenic origin simply reflect coexistent cerebrovascular disease.