The importance of anosmia, ageusia and age in community presentation of symptomatic and asymptomatic SARS-CoV-2 infection in Louisiana, USA; a cross-sectional prevalence study.

摘要: Abstract Objective While many seroprevalence studies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been performed, few are demographically representative. This investigation focused on defining the nature and frequency symptomatic asymptomatic SARS-CoV-2 infection in a representative, cross-sectional sample communities Louisiana, USA. Methods A 4778 adults from New Orleans Baton Rouge, Louisiana were given survey symptoms co-morbidities, nasopharyngeal swab to test for active (PCR), blood draw past (IgG). Odds ratios, cluster analysis, quantification virus antibody, linear modelling used understand whether certain associated with positive test, how grouped together, or antibody varied by symptom status, being was different across age span. Results Reported anosmia/ageusia strongly test; 40.6% (93/229) tested versus 4.8% (218/4549) positivity those who did not report (OR 13.6, 95% CI 10.1–18.3). Of people positive, 47.3% (147/311) completely asymptomatic. Symptom presentation clustered into three groups; low/no (0.4 ± 0.9, mean ± SD), highly (7.5 ± 1.9) moderately (4.0 ± 1.5). Quantity lower group (cycle number 23.3 ± 8.3 17.3 ± 9.0; p  Conclusion Anosmia/ageusia can be differentiate other illnesses, and, high ratio individuals, contact tracing should include without symptoms. Regular testing congregant settings over 60 years may help mitigate spread.