Mizoroki−Heck Coupling Using Immobilized Molecular Precatalysts: Leaching Active Species from Pd Pincers, Entrapped Pd Salts, and Pd NHC Complexes

摘要: The Mizoroki−Heck reaction is a palladium-catalyzed of both practical importance and scientific significance. Two challenges currently faced by practitioners the Heck other coupling reactions are (i) minimizing costs associated with this developing high TON catalysts or facilitating catalyst recovery (ii) elucidating nature active species when using various different precatalysts. These two challenges, one fundamental, served as our motivation in studies immobilized molecular palladium(II) complexes precatalysts reactions. This Forum Article describes investigations area, highlighting approach to elucidation combining kinetic poisoning several related precatalysts, development new, selective poisons, quest for stable, recyclable supported Heck, Suzuki, Sonogashira catalysts. Under high-tem...