Methods for production of oligonucleotides
作者： Jakob Schwalbe Lohmann , Jorn Erland Koch , Magnus Stougaard
DOI:
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摘要: The present invention relates to production of oligonucleotides using rolling circle replication, wherein synthesised multimeric are reduced mononucleotides a nicking cassette. Thus, the provides method for oligonucleotides, enabling efficient amplification at lengths up least 1000 nucleotides and in high amounts contained within
google.de 参考文章(60)
H Lassmann, M Schmied, H P Hartung, H Breitschopf, R Gold, K V Toyka, G Giegerich, Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques. Laboratory Investigation. ,vol. 71, pp. 219- 225 ,(1994)
Timothy O'connell, Octavian Schatz, Nucleic acid linkers and use thereof in gene synthesis ,(2002)
Christophe Escude, Thibaut Roulon, Therese Garestier, Claude Helene, Method for circularizing oligonucleotides around a double stranded nucleic acid, resulting structures and uses thereof ,(2000)
Jolanta Maluszynska, Piotr Luchniak, Maria J Olszewska, Different DNA methylation pattern in A and B chromosomes of Crepis capillaris detected by in situ nick-translation. Comparison with molecular methods. Folia Histochemica Et Cytobiologica. ,vol. 40, pp. 325- ,(2002)
Jerry L Ruth, David A. Driver, Circular extension for generating multiple nucleic acid complements ,(1991)
Jeffrey I. Auerbach, Amplification of nucleic acid molecules via circular replicons ,(2000)
George T. Walker, James L. Schram, Exonuclease mediated strand displacement amplification ,(1992)
Marleen Walner, Elazar Rabbani, Jack Coleman, Jannis G. Stavrianopolous, James J. Donegan, Processes useful for nucleic acid amplification and sequencing, and for the production of nucleic acid having decreased thermodynamic stability ,(1999)
Harash Kumar Narang, Oligonucleotides and their use in an assay for encephalopathies ,(1995)