Therapeutic role of lymph node resection in endometrioid corpus cancer

摘要: BACKGROUND. The purpose of the current study was to determine potential therapeutic role lymphadenectomy in women with endometrioid corpus cancer. METHODS. Demographic and clinicopathologic information were obtained from Surveillance, Epidemiology, End Results Program between 1988–2001. Data analyzed using Kaplan-Meier methods Cox proportional hazards regression. RESULTS. In all, 12,333 (median age, 64) underwent surgical staging lymph node assessment, including 9,009, 1,211, 1,223, 890 Stage I-IV disease. Over time intervals 1988–1992, 1993–1997, 1998–2001, percentage patients undergoing increased 22.6%, 29.6%, 40.9% (P 20) associated improved 5-year disease-specific survivals across all 5 groups at 75.3%, 81.5%, 84.1%, 85.3%, 86.8%, respectively < .001). For IIIC-IV nodal disease, extent resection significantly survival 51.0%, 53.0%, 60.0%, 72.0%, However, no significant benefit low-risk could be demonstrated (Stage IA, grades; IB, Grades 1 2 disease; P = .23). In multivariate analysis, a more extensive remained prognostic factor for intermediate/high-risk after adjusting other factors year diagnosis, stage, grade, adjuvant radiotherapy, presence positive nodes .001). CONCLUSIONS. The findings suggest that improves uterine cancer. Cancer 2006. © 2006 American Society.