Biphosphonate-associated osteonecrosis can be controlled by nonsurgical management.
作者： Lucio Montebugnoli , Laura Felicetti , Davide Bartolomeo Gissi , Angelo Pizzigallo , Gian Andrea Pelliccioni
DOI: 10.1016/J.TRIPLEO.2007.01.008
关键词:
摘要: Sixteen patients with jaw biphosphonate-osteonecrosis and exposed bone areas were subdivided into 2 treatment groups. The first group (7 patients) underwent superficial or radical surgical therapy, while the second (9 antibiotic treatment. A slight reduction of necrotic was observed in 5 7 group, whereas no change remaining at 22- 24-month follow-up. 9 5- statistical analysis showed that regimen did not significantly influence dimensional bone. preliminary results seem to suggest biphosphonate-associated osteonecrosis can be well controlled by a nonsurgical protocol consisting long-term administration antibiotics.
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