Landau Kleffner Syndrome: Neuroradiology Aspect

摘要: 1.1 Magnetoencephalography The first recording of electromagnetic fields in the brain, or magnetoencephalography (MEG), were performed 1968 at Massachussets Institute Techonology Boston, by David Cohen team, exploring alpha rhythm with aid a single sensor machine (Cohen,1968). In 1972 again studied normal subjects, and response to hyperventilation patient partial complex seizures (Cohen, 1972). Until mideighties, MEG equipment had that practice meant, addition spatial limitation study, is was necessary prolong studies excessively until it possible gather required data. Magnetoencefalography, up 148 channels, has been more useful dipole localization evaluating transcallosal spread than traditional EEG, given limited channels 10-20 system. At present, over hundred installations worldwide contribute our knowledge about function development human brain (Pateau, 2002). Most have conducted adult but some data already exist on children. Pediatric mainly focused epilepsy surgery, Landau-Kleffner syndrome related disorders, sensory cortex properties progressive myoclonus epilepsies, dyslexia. noninvasive technique measure magnetic generated intracellular current flow dendrites pyramidal neurons cortex. fluctuations field produced this can be recorded from outside scalp subsequently used locate cortical generators activity temporal resolution measured millisecond. These characteristic made an invalidly tool study centers cognitive functions. way, served show there neuronal dynamic involved language process (Pulvermuller,et al.,2003;Wilson,et al.,2005;Pammer,et al.,2004) that, measuring derived helps sources electrical electric manner(Ray & Bowyer,2010). Despite being relatively new technique, fast becoming essential for clinical physicians, including neurophysiologist, give accurate diagnosis Although main applications are found area presurgical evaluation,