Differential Hybridization Analysis as a Tool to Study Prostatic Cancer Metastasis

作者: Jack A. Schalken , Marion J. G. Bussemakers

DOI: 10.1007/978-1-4615-3704-5_38

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摘要: The progression of prostate cancer can be described in terms growth rate, hormone responsiveness, histology and metastatic ability. Some these parameters interdependent. Clearly, ability tumor cells is clinically most significant. It this process which primary spread through the body grow out at secondary sites that leads to much lethality due cancer. For clinical consequences established disease are profound, since no curative therapy available (1). Systemic palliative methods, based on androgen ablation, usually succesful, but limited duration. outgrowth insensitive inevitable, will eventually result patients death (2).

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