Effects of Recombination Rate and Gene Density on Transposable Element Distributions in Arabidopsis thaliana

作者: Thomas E. Bureau , Stephen I. Wright , Newton Agrawal

DOI: 10.1101/GR.1281503

关键词:

摘要: Transposable elements (TEs) comprise a major component of eukaryotic genomes, and exhibit striking deviations from random distribution across the genomes studied, including humans, flies, nematodes, plants. Although considerable progress has been made in documenting these patterns, causes are subject to debate. Here, we use genome sequence Arabidopsis thaliana test for importance competing models natural selection against TE insertions. We show that, despite accumulation near centromeres, recombination does not generally correlate with abundance, suggesting that ectopic influence A. thaliana. In contrast, consistent negative correlation between gene density strong under-representation insertions introns suggest disruption expression is playing more important role High rates self-fertilization may reduce rate structuring inbreeding organisms such as Caenorhabditis elegans.

参考文章(53)
J. L. Jakubczak, W. D. Burke, T. H. Eickbush, Retrotransposable elements R1 and R2 interrupt the rRNA genes of most insects. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 3295- 3299 ,(1991) , 10.1073/PNAS.88.8.3295
Positive Association between copia Transposition Rate and Copy Number in Drosophila melanogaster Proceedings of The Royal Society B: Biological Sciences. ,vol. 263, pp. 823- 831 ,(1996) , 10.1098/RSPB.1996.0122
Anne-Valérie Gendrel, Zachary Lippman, Cristy Yordan, Vincent Colot, Robert A Martienssen, Dependence of Heterochromatic Histone H3 Methylation Patterns on the Arabidopsis Gene DDM1 Science. ,vol. 297, pp. 1871- 1873 ,(2002) , 10.1126/SCIENCE.1074950
Katrien M Devos, James KM Brown, Jeffrey L Bennetzen, Genome size reduction through illegitimate recombination counteracts genome expansion in Arabidopsis. Genome Research. ,vol. 12, pp. 1075- 1079 ,(2002) , 10.1101/GR.132102
Patrick S. Schnable, An-Ping Hsia, Basil J. Nikolau, Genetic recombination in plants Current Opinion in Plant Biology. ,vol. 1, pp. 123- 129 ,(1998) , 10.1016/S1369-5266(98)80013-7
MARTIN T. MORGAN, Transposable element number in mixed mating populations. Genetics Research. ,vol. 77, pp. 261- 275 ,(2001) , 10.1017/S0016672301005067
Carolina Bartolomé, Xulio Maside, Brian Charlesworth, On the Abundance and Distribution of Transposable Elements in the Genome of Drosophila melanogaster Molecular Biology and Evolution. ,vol. 19, pp. 926- 937 ,(2002) , 10.1093/OXFORDJOURNALS.MOLBEV.A004150
Stefan A. Surzycki, William R. Belknap, CHARACTERIZATION OF REPETITIVE DNA ELEMENTS IN ARABIDOPSIS Journal of Molecular Evolution. ,vol. 48, pp. 684- 691 ,(1999) , 10.1007/PL00006512
Paul M Harrison, Nathaniel Echols, Mark B Gerstein, Digging for dead genes: an analysis of the characteristics of the pseudogene population in the Caenorhabditis elegans genome Nucleic Acids Research. ,vol. 29, pp. 818- 830 ,(2001) , 10.1093/NAR/29.3.818
Deborah Charlesworth, Stephen I Wright, Breeding systems and genome evolution. Current Opinion in Genetics & Development. ,vol. 11, pp. 685- 690 ,(2001) , 10.1016/S0959-437X(00)00254-9