Role for dithiolopyrrolones in disrupting bacterial metal homeostasis
作者： Andrew N. Chan , Anthony L. Shiver , Walter J. Wever , Sayyeda Zeenat A. Razvi , Matthew F. Traxler
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摘要: … NDM-1 contains two active site zincs and requires at least one for imipenem hydrolysis (25). We reconstituted NDM… chelation of metal ions can simultaneously alter metal availability and …
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