Complications and mortality in older surgical patients in Australia and New Zealand (the REASON study): a multicentre, prospective, observational study*

摘要: We conducted a prospective study of non-cardiac surgical patients aged 70 years or more in 23 hospitals Australia and New Zealand. studied 4158 consecutive whom 2845 (68%) had pre-existing comorbidities. By day 30, 216 (5%) died, 835 (20%) suffered complications; 390 (9.4%) were admitted to the Intensive Care Unit. Pre-operative factors associated with mortality included: increasing age (80-89 years: OR 2.1 (95% CI 1.6-2.8), p < 0.001; 90+ 4.0 2.6-6.2), 0.001); worsening ASA physical status (ASA 3: 3.1 1.8-5.5), 4: 12.4 6.9-22.2), pre-operative plasma albumin 30 g.l⁻¹ (OR: 2.5 1.8-3.5), non-scheduled surgery (OR 1.8 1.3-2.5), 0.001). Complications acute renal impairment 3.3 2.1-5.0), unplanned Unit admission 1.9-4.9), systemic inflammation 1.7-3.7), Patient often stronger association than type surgery. Strategies are needed reduce complications older patients.