摘要: Beta,gamma-meATP is a potent and stable partial agonist at P2X1, P2X3 P2X5 receptors. Its action stereo-selective (D ≫ L), but not P2X1 receptors = L). It has little or no known effects other P2X P2Y
sci-hub.st 参考文章(11)
B. F. King, A. Townsend-Nicholson, S. S. Wildman, T. Thomas, K. M. Spyer, G. Burnstock, Coexpression of Rat P2X2and P2X6Subunits inXenopusOocytes The Journal of Neuroscience. ,vol. 20, pp. 4871- 4877 ,(2000) , 10.1523/JNEUROSCI.20-13-04871.2000
G Buell, R J Evans, A Surprenant, R A North, C Lewis, S Valera, Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2x purinoceptors). Molecular Pharmacology. ,vol. 48, pp. 178- 183 ,(1995)
Scott S. Wildman, Sean G. Brown, Mary Rahman, Carole A. Noel, Linda Churchill, Geoffrey Burnstock, Robert J. Unwin, Brian F. King, Sensitization by extracellular Ca (2+) of rat P2X 5 receptor and its pharmacological properties compared with rat P2X 1 Molecular Pharmacology. ,vol. 62, pp. 957- 966 ,(2002) , 10.1124/MOL.62.4.957
M. G. Rae, E. G. Rowan, C. Kennedy, Pharmacological properties of P2X3-receptors present in neurones of the rat dorsal root ganglia British Journal of Pharmacology. ,vol. 124, pp. 176- 180 ,(1998) , 10.1038/SJ.BJP.0701803
G. Burnstock, C. Kennedy, Is there a basis for distinguishing two types of P2-purinoceptor? General Pharmacology-the Vascular System. ,vol. 16, pp. 433- 440 ,(1985) , 10.1016/0306-3623(85)90001-1
Gunter Lambrecht, Kirsten Braun, Susanne Damer, Matthias Ganso, Caren Hildebrandt, Heiko Ullmann, Matthias Kassack, Peter Nickel, Structure-activity relationships of suramin and pyridoxal-5'-phosphate derivatives as P2 receptor antagonists. Current Pharmaceutical Design. ,vol. 8, pp. 2371- 2399 ,(2002) , 10.2174/1381612023392973
Geoffrey Burnstock, Alexei Verkhratsky, Receptors for Purines and Pyrimidines Pharmacological Reviews. ,vol. 50, pp. 413- 492 ,(1998) , 10.1007/978-3-642-28863-0_5
WA Catterall, KG Chandy, DE Clapham, GA Gutman, F Hofmann, AJ Harmar, Darrell R Abernethy, M Spedding, None, International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels Pharmacological Reviews. ,vol. 55, pp. 573- 574 ,(2003) , 10.1124/PR.55.4.5
R. Alan North, Annmarie Surprenant, Pharmacology of cloned P2X receptors. Annual Review of Pharmacology and Toxicology. ,vol. 40, pp. 563- 580 ,(2000) , 10.1146/ANNUREV.PHARMTOX.40.1.563
Baljit S. Khakh, Geoffrey Burnstock, R. Alan North, Charles Kennedy, Mark Voigt, Brian F. King, Patrick P. A. Humphrey, Philippe Séguéla, International Union of Pharmacology. XXIV. Current Status of the Nomenclature and Properties of P2X Receptors and Their Subunits Pharmacological Reviews. ,vol. 53, pp. 107- 118 ,(2001)