Latent Tuberculosis Infection (LTBI) and Its Potential Targets: An Investigation into Dormant Phase Pathogens.

作者: Gopichand Gutti , Karan Arya , Sushil Kumar Singh

DOI: 10.2174/1389557519666190625165512

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摘要: One-third of the world's population harbours latent tuberculosis infection (LTBI) with a lifetime risk reactivation. Although, treatment LTBI relies significantly on first-line therapy, identification novel drug targets and therapies are emerging focus for researchers across globe. The current review provides an insight into infection, diagnostic methods epigrammatic explanations potential molecular dormant phase bacilli. This study also includes preclinical clinical aspects tubercular infections new approaches in antitubercular discovery.

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