Infrared Spectrometry Applied to Steroid Structure and Metabolism

作者: R.Norman Jones , Konrad Dobriner

DOI: 10.1016/S0083-6729(08)60832-8

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摘要: Publisher Summary This chapter illustrates how infrared spectrometry has been utilized in the elucidation of structure steroids and steroid metabolism. The specificity spectrum is finding application connection with problems synthesis. It made possible detection identification individual and, combination adsorption chromatography, permitted qualitative quantitative analyses complex mixtures to be performed. By these methods, a considerable number new have isolated from human urine. introduction deuterium atoms modifies spectra valuable supplement mass detection, analysis, enriched compounds. Correlations between positions certain absorption bands molecular established. These permit presence all functional groups which commonly occur recognized. In case carbonyl double bonds, more specific information can also derived as their location molecule. use microtechniques, it obtain this on quantities material order 25 μg.

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