Botulinum toxin therapy for treatment of spasticity in multiple sclerosis: review and recommendations of the IAB-Interdisciplinary Working Group for Movement Disorders task force
作者： Dirk Dressler , Roongroj Bhidayasiri , Saeed Bohlega , Abderrahmane Chahidi , Tae Mo Chung
DOI: 10.1007/S00415-016-8304-Z
关键词:
摘要: Botulinum toxin (BT) therapy is an established treatment of spasticity due to stroke. For multiple sclerosis (MS) this not the case. IAB-Interdisciplinary Working Group for Movement Disorders formed a task force explore use BT MS spasticity. A formalised PubMed literature search produced 55 publications (3 randomised controlled trials, 3 interventional studies, 11 observational 2 case 35 reviews, 1 guideline) all unanimously favouring There no reason believe that should be less effective and safe in than it stroke Recommendations include update current prevalence its clinical features according classifications used movement disorders. Immunological data on patients already treated analysed with respect frequencies relapses antibody formation. Registration authorities expand registration regardless aetiology. specialists consider symptomatic
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