Lysyl oxidase isoforms in gastric cancer

作者: Carolina Añazco , Fernando Delgado-López , Paulina Araya , Ileana González , Erik Morales

DOI: 10.2217/BMM-2016-0075

关键词:

摘要: Gastric cancer (GC) is the fifth most frequent in world and shows highest incidence Latin America Asia. An increasing amount of evidence demonstrates that lysyl oxidase isoforms, a group extracellular matrix crosslinking enzymes, should be considered as potential biomarkers therapeutic targets GC. In this review, we focus on expression levels its functions clinical implications Finding novel proteins related to processing these enzymes might helpful design new therapies, which, combination with classic pharmacology, could used delay progress aggressive offer wider temporal window for intervention.

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