IL-6 Potentiates Tumor Resistance to Photodynamic Therapy (PDT)
作者： Craig M. Brackett , Barbara Owczarczak , Kimberley Ramsey , Patricia G. Maier , Sandra O. Gollnick
DOI: 10.1002/LSM.21107
关键词:
摘要: Background and Objective Photodynamic therapy (PDT) is an anticancer modality approved for the treatment of early disease palliation late stage disease. PDT tumors results in generation acute inflammatory response. The extent duration response dependent upon regimen employed characterized by rapid induction proinflammatory cytokines, such as IL-6, activation mobilization innate immune cells. importance cells long-term control tumor growth has been well defined. In contrast role IL-6 unclear. Previous studies have shown that can diminish or no effect on antitumor efficacy.
sci-hub.se 参考文章(44)
MLADEN KORBELIK, Induction of tumor immunity by photodynamic therapy. Journal of Clinical Laser Medicine & Surgery. ,vol. 14, pp. 329- 334 ,(1996) , 10.1089/CLM.1996.14.329
Sandra O. Gollnick, Barbara Owczarczak, Barbara W. Henderson, David A. Musser, Xiaonan Liu, Altered Expression of Interleukin 6 and Interleukin 10 As a Result of Photodynamic Therapy in Vivo Cancer Research. ,vol. 57, pp. 3904- 3909 ,(1997)
Barbara W. Henderson, William R. Potter, Patrick B. Malone, Thomas S. Mang, Thomas J. Dougherty, Stephen M. Waldow, Tumor destruction and kinetics of tumor cell death in two experimental mouse tumors following photodynamic therapy. Cancer Research. ,vol. 45, pp. 572- 576 ,(1985)
Claire J Greenhill, Stefan Rose-John, Rami Lissilaa, Walter Ferlin, Matthias Ernst, Paul J Hertzog, Ashley Mansell, Brendan J Jenkins, None, IL-6 Trans-Signaling Modulates TLR4-Dependent Inflammatory Responses via STAT3 Journal of Immunology. ,vol. 186, pp. 1199- 1208 ,(2011) , 10.4049/JIMMUNOL.1002971
Simon A. Jones, Directing transition from innate to acquired immunity: defining a role for IL-6. Journal of Immunology. ,vol. 175, pp. 3463- 3468 ,(2005) , 10.4049/JIMMUNOL.175.6.3463
Hongyan Du, Boon-Huat Bay, Ratha Mahendran, Malini Olivo, Hypericin-mediated photodynamic therapy elicits differential interleukin-6 response in nasopharyngeal cancer Cancer Letters. ,vol. 235, pp. 202- 208 ,(2006) , 10.1016/J.CANLET.2005.04.013
Jürgen Scheller, Stefan Rose-John, Interleukin-6 and its receptor: from bench to bedside. Medical Microbiology and Immunology. ,vol. 195, pp. 173- 183 ,(2006) , 10.1007/S00430-006-0019-9
Sue S. Yom, Theresa M. Busch, Joseph S. Friedberg, E. Paul Wileyto, Deborah Smith, Eli Glatstein, Stephen M. Hahn, Elevated Serum Cytokine Levels in Mesothelioma Patients Who Have Undergone Pleurectomy or Extrapleural Pneumonectomy and Adjuvant Intraoperative Photodynamic Therapy Photochemistry and Photobiology. ,vol. 78, pp. 75- 81 ,(2003) , 10.1562/0031-8655(2003)078<0075:ESCLIM>2.0.CO;2
David A. Bellnier, William R. Greco, John C. Parsons, Allan R. Oseroff, Alex Kuebler, Thomas J. Dougherty, An assay for the quantitation of Photofrin in tissues and fluids. Photochemistry and Photobiology. ,vol. 66, pp. 237- 244 ,(1997) , 10.1111/J.1751-1097.1997.TB08649.X
Philaretos C. Kousis, Barbara W. Henderson, Patricia G. Maier, Sandra O. Gollnick, Photodynamic therapy enhancement of antitumor immunity is regulated by neutrophils Cancer Research. ,vol. 67, pp. 10501- 10510 ,(2007) , 10.1158/0008-5472.CAN-07-1778