Ethnic minority under-representation in clinical trials. Whose responsibility is it anyway?

摘要: Ethnic minority people are frequently under‐represented in clinical trials. This potentially affects the generalisability/external validity of trial findings. not only has important repercussions regarding safety and efficacy new drug use ethnic groups, but also reduces opportunities for subgroup analysis. There can be no scientific basis excluding this group from Aims to provide a mix theoretical empirical debates, order make sense exclusion trials, suggest possibility change. Recommends that educational programmes should directed at investigators funding bodies, increase their awareness under‐representation Ethics committees could redress inequality by providing guidance investigators, being more rigorous about reviewing protocols. Provides set guidelines “enlighten” aid health professionals working with ethnic, linguistic culturally diverse populations. The require additional work have cost implications. Argues allowed as an acceptable excuse