Expression of miR-711 and mechanism of proliferation and apoptosis in human gastric carcinoma.
作者： Sheng‑Xing Zhu , Xian‑Zhou Tong , Shuijun Zhang
DOI: 10.3892/OL.2018.7736
关键词:
摘要: MicroRNAs (miRs) are involved in many aspects of cell biology, including proliferation and apoptosis, two critical tumor biology. We investigated the effect miR-711 on Bcl-2 expression human MGC803 gastric cancer cells mechanism proliferation, invasion. Expression was significantly increased adenocarcinoma compared to adjacent normal tissue. Inhibition decreased Bcl-2, invasion ability, apoptosis. The protein correlated with clinical staging, lymph node metastasis, differentiation patients cancer. positively suggesting that co-regulated development
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