Renal cell carcinoma and tumour thrombus in the inferior vena cava: clinical outcome of 98 consecutive patients and the prognostic value of preoperative parameters

摘要: To evaluate the outcome of patients after nephrectomy and removal tumour thrombus to assess prognostic value preoperative parameters. Ninety-eight who were surgically treated between 2002 2011 included. Patients’ charts reviewed, with renal cell carcinoma (RCC) concomitant in vein (RV) compared those extended inferior vena cava (IVC) thrombus. Wilcoxon rank-sum test, Kaplan–Meier analysis uni- multivariate Cox regression used for statistical evaluation. Follow-up was 36 months (20–122 months), 5-year disease-specific survival (DSS) overall 68.4 54.1 %, respectively. Patients (levels 2–4) had higher intraoperative transfusion rates concentrated red cells (CRC) fresh-frozen plasma (FFP) confined RV (CRC: 5.8 vs. 1.5, p < 0.0001; FFP: 2.3 0.4, p = 0.0032). Surgery time (190 107 min, p < 0.0001), duration hospitalisation (16 11 days, p = 0.0269), serum phosphate (3.64 3.29 mmol/l, p = 0.0369) CRP levels (6.7 4.4 mg/dl, p = 0.0194) as well aPTT increased (33.7 29.6 s, p = 0.0059) disease. In analysis, presence distant metastasis (p = 0.03) lymphovascular invasion (p = 0.001), high platelet counts (p = 0.001) potassium (p = 0.032) proved be independent factors. The surgical treatment RCC or IVC has favourable results. Extended disease requires multidisciplinary approach. High are associated reduced DSS.