Reciprocal activation of hypoxia-inducible factor (HIF)-2α and the zinc-ZIP8-MTF1 axis amplifies catabolic signaling in osteoarthritis

作者: M. Lee , Y. Won , Y. Shin , J.-H. Kim , J.-S. Chun

DOI: 10.1016/J.JOCA.2015.07.016

关键词:

摘要: … MTF1-induced HIF-2α upregulation amplifies MTF1 catabolic signaling during OA pathogenesis. (A) MTF1 … in chondrocytes infected with Ad-Zip8 or Ad-Mtf1. (B) qRT-PCR analysis of …

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