Oropharyngeal carcinoma : what the dentist should know

摘要: SUMMARY HPV-related oropharyngeal carcinoma (OPC) is a clinically and molecularly distinct form of squamous cell (SCC) which has recently shown dramatic increase in global incidence. The aetiology, clinical presentation overall prognosis differ from conventional tobacco alcohol related SCC the oral cavity. OPC seen subset younger predominantly male patients. Acquisition highrisk HPV subtypes to sex practices with multiple partners. originates deep within tonsillar crypts hinders early detection. Patients present advanced disease frequent cervical lymph node metastases. Despite its aggressive nature, remains excellent compared SCC. increased incidence significance general dentist should always be considered differential diagnosis young, otherwise healthy, patient persistent enlargement. Older patients history usage consumption may also oropharynx. Potentially malignant precede tumour development at this site such cases. Clinical examination oropharynx therefore performed as part routine dental consultation.