Education, Cognitive Test Scores, and Black‐White Differences in Dementia Risk

摘要: OBJECTIVES: To compare dementia risks of elderly black and white subjects to determine whether differences in education cognitive test scores contribute the inconsistency reported between these groups. DESIGN: Longitudinal, 6-year follow-up. PARTICIPANTS: Two thousand seven hundred eighty-six older Cardiovascular Health Study. MEASUREMENTS: Age, (>10 years vs ≤10 years), Modified Mini-Mental State Examination score (3MS, ≤85 >85). Potential confounders were sex, depression, apolipoprotein E4 genotype, vascular disease, baseline magnetic resonance imaging changes. RESULTS: White with low high had twice risk (95% confidence interval (CI)=1.5–2.4 95% CI=1.4–2.7); five times CI=3.4–7.7). Likewise, for 3MSE scores, 6.7 CI=4.7–9.7) 2.7 CI=2.2–3.5) as scores. Finally, Cox models, there was no significant black-white difference after adjustment all 3MSE. CONCLUSION: Black race associated greater even other potential confounders. This markedly attenuated screening The apparent effect may reflect gaps quality or trajectory impaired function experienced by two groups. Future investigations might take findings into consideration design studies evaluating risk.