The effect of intrathecal baclofen treatment on activities of daily life in children and young adults with cerebral palsy and progressive neurological disorders.

作者: Laura Bonouvrié , Jules Becher , Dan Soudant , Annemieke Buizer , Willem van Ouwerkerk

DOI: 10.1016/J.EJPN.2016.02.013

关键词:

摘要: Abstract Introduction Intrathecal baclofen (ITB) treatment is applied in patients with spastic cerebral palsy (SCP), dystonic (DCP) and progressive neurological disease (PND). Our aim was to investigate whether ITB has a different effect on activities of daily life (ADL) these groups. Method A retrospective cross-sectional survey conducted using questionnaire assess the qualitative (Likert scale) domains functioning (mobility, personal care, communication, comfort) satisfaction results. Groups were compared non-parametric statistics. Results Questionnaires completed for 68 (39 SCP, 13 DCP, 16 PND). Satisfaction scores relatively high all groups (7–8) positive care communication similar The PND group had shortest follow-up scored significantly less favourably mobility comfort. Discussion This first study show that effects stable disease. decrease likely due nature comfort between mainly smaller startles group.

参考文章(26)
A Sghedoni, F Lombardi, S Alboresi, A Ferrari, E Pedroni, New definitions of 6 clinical signs of perceptual disorder in children with cerebral palsy: an observational study through reliability measures. European Journal of Physical and Rehabilitation Medicine. ,vol. 50, pp. 709- 716 ,(2014)
A Leland Albright, Margaret J Barry, David H Shafron, Susan S Ferson, Intrathecal baclofen for generalized dystonia Developmental Medicine & Child Neurology. ,vol. 43, pp. 652- 657 ,(2001) , 10.1017/S0012162201001190
Anna Ward, Suzie Hayden, Mark Dexter, Adam Scheinberg, Continuous intrathecal baclofen for children with spasticity and/or dystonia: Goal attainment and complications associated with treatment. Journal of Paediatrics and Child Health. ,vol. 45, pp. 720- 726 ,(2009) , 10.1111/J.1440-1754.2009.01601.X
Hakan Senaran, Suken A. Shah, Ana Presedo, Kirk W. Dabney, Joseph W. Glutting, Freeman Miller, The risk of progression of scoliosis in cerebral palsy patients after intrathecal baclofen therapy. Spine. ,vol. 32, pp. 2348- 2354 ,(2007) , 10.1097/BRS.0B013E3181557252
Djamel Ben Smail, Claire Jacq, Pierre Denys, Bernard Bussel, Intrathecal baclofen in the treatment of painful, disabling spasms in Friedreich's ataxia. Movement Disorders. ,vol. 20, pp. 758- 759 ,(2005) , 10.1002/MDS.20405
Marjanke A. Hoving, Elisabeth P.M. van Raak, Geert H.J.J. Spincemaille, Liesbeth J. Palmans, Jules G. Becher, Johan S.H. Vles, Efficacy of intrathecal baclofen therapy in children with intractable spastic cerebral palsy: A randomised controlled trial European Journal of Paediatric Neurology. ,vol. 13, pp. 240- 246 ,(2009) , 10.1016/J.EJPN.2008.04.013
Georges F. Vles, Dan L. Soudant, Marjanke A. Hoving, R. Jeroen Vermeulen, Laura A. Bonouvrié, Robert J. van Oostenbrugge, Johan S.H. Vles, Long-term follow-up on continuous intrathecal Baclofen therapy in non-ambulant children with intractable spastic Cerebral Palsy. European Journal of Paediatric Neurology. ,vol. 17, pp. 639- 644 ,(2013) , 10.1016/J.EJPN.2013.06.003
Laura A. Bonouvrié, Petra E.M. van Schie, Jules G. Becher, Willem J.R. van Ouwerkerk, Alexander Reeuwijk, R. Jeroen Vermeulen, Effects of intrathecal baclofen on daily care in children with secondary generalized dystonia: a pilot study. European Journal of Paediatric Neurology. ,vol. 15, pp. 539- 543 ,(2011) , 10.1016/J.EJPN.2011.05.003
Collette Staal, Amy Arends, Sam Ho, A Self-Report of Quality of Life of Patients Receiving Intrathecal Baclofen Therapy Rehabilitation Nursing. ,vol. 28, pp. 159- 163 ,(2003) , 10.1002/J.2048-7940.2003.TB02050.X