Cladribine in the treatment of hairy-cell leukaemia.
作者： Grant R Goodman , Ernest Beutler , Alan Saven
DOI: 10.1016/S1521-6926(02)00089-0
关键词:
摘要: Abstract Cladribine, a purine nucleoside analogue, is safe and effective treatment for patients with hairy-cell leukaemia. It administered at dose of 0.09 mg/kg daily as continuous intravenous infusion over 7 days. This chapter discusses the history, rationale, chemical structure mechanism action cladribine. The indications therapy guidelines clinical usage are reviewed. response leukaemia to cladribine, acute chronic complications risk second malignancies summarized. concludes section on salvage therapy.
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