PF1092A, B and C, new nonsteroidal progesterone receptor ligands produced by Penicillium oblatum. I. Taxonomy of producing strain, fermentation, isolation and biological activities.
作者： YUJI TABATA , NAOKO MIIKE , MASAHIRO HATSU , YASUSHI KURATA , TAKASHI YAGUCHI
DOI: 10.7164/ANTIBIOTICS.50.304
关键词:
摘要: The structures of PF1092A (1), B (2) and C (3), new nonsteroidal progesterone receptor ligands produced by Penicillium oblatum, were elucidated spectroscopic analyses. These compounds possess an eremophilane-type sesquiterpene carbon skeleton differ only in that 1 2 are different monoacetates 3. absolute configurations 1-3 determined single crystal X-ray diffraction analysis the 4-bromobenzoyl ester measuring optical rotations acetylation products these compounds.
sci-hub.se 参考文章(17)
Y. Ishizaki, Y. Tanahashi, T. Takahashi, K. Tori, The structure of ligularenolide : A new sesquiterpene lactone of eremophilane type Tetrahedron. ,vol. 26, pp. 5387- 5393 ,(1970) , 10.1016/S0040-4020(01)98749-6
YUJI TABATA, MASAHIRO HATSU, YASUSHI KURATA, KAORI MIYAJIMA, MASATO TANI, TORU SASAKI, YOSHIO KODAMA, TAKASHI TSURUOKA, SHOJI OMOTO, PF1092A, B and C, new nonsteroidal progesterone receptor ligands produced by Penicillium oblatum. II. Physico-chemical properties and structure elucidation. The Journal of Antibiotics. ,vol. 50, pp. 309- 313 ,(1997) , 10.7164/ANTIBIOTICS.50.309
Steven M. Grunberg, Martin H. Weiss, Irving M. Spitz, Jamshid Ahmadi, Alfredo Sadun, Christy A. Russell, Lois Lucci, Lani L. Stevenson, Treatment of unresectable meningiomas with the antiprogesterone agent mifepristone. Journal of Neurosurgery. ,vol. 74, pp. 861- 866 ,(1991) , 10.3171/JNS.1991.74.6.0861
L. E. Caird, V. Reid-Thomas, W. J. Hannan, S. Gow, A. F. Glasier, Oral progestogen‐only contraception may protect against loss of bone mass in breast‐feeding women Clinical Endocrinology. ,vol. 41, pp. 739- 745 ,(1994) , 10.1111/J.1365-2265.1994.TB02788.X
E.I. Barengolts, H.F. Gajardo, T.J. Rosol, J.J. D'Anza, M. Pena, J. Botsis, S.C. Kukreja, Effects of progesterone on postovariectomy bone loss in aged rats Journal of Bone and Mineral Research. ,vol. 5, pp. 1143- 1147 ,(2009) , 10.1002/JBMR.5650051109
John I. Pitt, The genus Penicillium and its teleomorphic states Eupenicillium and Talaromyces The genus Penicillium and its teleomorphic states Eupenicillium and Talaromyces.. ,(1979)
Rainer Rupprecht, Charlotte A.E. Hauser, Thorsten Trapp, Florian Holsboer, Neurosteroids: Molecular mechanisms of action and psychopharmacological significance The Journal of Steroid Biochemistry and Molecular Biology. ,vol. 56, pp. 163- 168 ,(1996) , 10.1016/0960-0760(95)00233-2
Ana Alvarez Murphy, Penny Z. Castellano, RU486: pharmacology and potential use in the treatment of endometriosis and leiomyomata uteri. Current Opinion in Obstetrics & Gynecology. ,vol. 6, pp. 269- 278 ,(1994) , 10.1097/00001703-199406000-00012
Donald W. Combs, Kimberly Reese, Lyndon A. M. Cornelius, Joseph W. Gunnet, Ellen V. Cryan, Kay S. Granger, Jerold J. Jordan, Keith T. Demarest, Nonsteroidal progesterone receptor ligands. 2. High-affinity ligands with selectivity for bone cell progesterone receptors. Journal of Medicinal Chemistry. ,vol. 38, pp. 4880- 4884 ,(1995) , 10.1021/JM00025A004
KEN-ICHI KURIHARA, KIYOSHI TANABE, RIE SHINEI, TSUNEO OKONOGI, YASUO OHTSUKA, SHOJI OMOTO, SHOHEI YASUDA, KUNIAKI TATSUTA, Synthesis of (±)-PF1092A, B, and C; New Nonsteroidal Progesterone Receptor Ligands The Journal of Antibiotics. ,vol. 50, pp. 360- 362 ,(1997) , 10.7164/ANTIBIOTICS.50.360