Relationship between structure and antibacterial activity in the fluoroquinolone series of compounds

作者: G. A. Mokrushina , V. N. Charushin , O. N. Chupakhin

DOI: 10.1007/BF02226387

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摘要: Considering the great number of publications related to fluoroquinolones, it is quite natural that this review cannot exhaustively summarize information on biological activity these compounds. This article directed primarily at specialists in organic chemistry acquaint them with general laws and trends governing relationship between structure derivatives 4-hydroxo-3-quinolinecarboxylic acid. The current interest promising class compounds fact other kinds activity, addition antibacterial action, have been discovered give us hope new preparations series will be synthesized used practice, which would offer a wide spectrum high level activity.

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