作者: Mich B. Hein , Andrew C. Hiatt , John H. Fitchen
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摘要: Targeting molecules are provided for use in delivering imaging agents to epithelial tissue. The targeting molecule comprises a polypeptide that forms closed covalent loop, contains at least three peptide domains having β-sheet character, each of the being separated by lacking character. specifically binds basolateral factor attached domain an cell surface causing internalization linked agent into cells. or may be amino acid sequence directs delivery carcinoma cell, nucleus, endoplasmic reticulum.