Prevalence of nosocomial infections in neonatal intensive care unit patients: Results from the first national point-prevalence survey.

摘要: Objectives: Patients admitted to neonatal intensive care units (NICUs) are at high risk of nosocomial infection. We conducted a national multicenter assessment infections in NICUs determine the prevalence infections, describe associated factors, and help focus prevention efforts. Study design: point survey 29 Pediatric Prevention Network NICUs. present on date were included. Data collected underlying diagnoses, therapeutic interventions/treatments, outcomes. Results: Of 827 patients surveyed, 94 (11.4%) had 116 NICU-acquired infections: bloodstream (52.6%), lower respiratory tract (12.9%), ear-nose-throat (8.6%), or urinary (8.6%). Infants with significantly birth weight (median 1006 g [range 441 4460 g] vs 1589 326 5480 g]; P < .001) longer median durations stay than those without (88 days 8 279 days] 32 1 483 days]; .001). Most common pathogens coagulase-negative staphylococci enterococci. central intravascular catheters (relative = 3.81, CI 2.32-6.25; receiving total parenteral nutrition 5.72, 3.45-9.49; greater Conclusions: This study documents urgent need for more effective interventions. (J Pediatr 2001;139:821–7)