作者: Noor Shabana , Valérie Cornilleau Pérès , Andrew Carkeet , Paul T.K Chew
DOI: 10.1016/S0039-6257(02)00401-0
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摘要: Most of the histopathological and psychophysical studies in glaucoma reveal a preferential damage to magnocellular (M) pathway although few them support parvocellular (P) as well. In glaucoma, visual fields are usually evaluated by conventional perimetry. However, it has been demonstrated that 20-40% ganglion cells lost before field defects detected using Therefore, new tests have recently designed order specifically isolate evaluate mechanisms impaired at early stages glaucoma. this context, several authors addressed issue motion perception under hypothesis predominant M is mediated mainly pathway. The results these depict large variation percentage patients showing anomalous perception. Overall, thresholds elevated both ocular hypertensive compared control subjects, irrespective stimulus size eccentricity. test which discriminates best between normal subjects identified perimetry similar, but sizes larger with central vision no correlation defect on loss performance does not necessarily existence specific deficit pathway, because some behavioral suggest P can also mediate It difficult conclude affected most do yield comparison other functions. Despite difficulties, localized eccentricities more than 15 degrees be considered promising diagnostic tool.