Motion perception in glaucoma patients: a review.

作者: Noor Shabana , Valérie Cornilleau Pérès , Andrew Carkeet , Paul T.K Chew

DOI: 10.1016/S0039-6257(02)00401-0

关键词:

摘要: Most of the histopathological and psychophysical studies in glaucoma reveal a preferential damage to magnocellular (M) pathway although few them support parvocellular (P) as well. In glaucoma, visual fields are usually evaluated by conventional perimetry. However, it has been demonstrated that 20-40% ganglion cells lost before field defects detected using Therefore, new tests have recently designed order specifically isolate evaluate mechanisms impaired at early stages glaucoma. this context, several authors addressed issue motion perception under hypothesis predominant M is mediated mainly pathway. The results these depict large variation percentage patients showing anomalous perception. Overall, thresholds elevated both ocular hypertensive compared control subjects, irrespective stimulus size eccentricity. test which discriminates best between normal subjects identified perimetry similar, but sizes larger with central vision no correlation defect on loss performance does not necessarily existence specific deficit pathway, because some behavioral suggest P can also mediate It difficult conclude affected most do yield comparison other functions. Despite difficulties, localized eccentricities more than 15 degrees be considered promising diagnostic tool.

参考文章(108)
Stephen M. Drance, The Early Field Defects in Glaucoma Investigative Ophthalmology & Visual Science. ,vol. 8, pp. 84- 91 ,(1969)
Christopher Girkin, Robert N. Weinreb, Pamela A. Sample, Charles F. Bosworth, Eytan Z. Blumenthal, Visual function-specific perimetry for indirect comparison of different ganglion cell populations in glaucoma. Investigative Ophthalmology & Visual Science. ,vol. 41, pp. 1783- 1790 ,(2000)
Robert N. Weinreb, Pamela A. Sample, Color perimetry for assessment of primary open-angle glaucoma. Investigative Ophthalmology & Visual Science. ,vol. 31, pp. 1869- 1875 ,(1990)
Lars Frisén, The unidirectionality of cerebral polyopia. Journal of clinical neuro-ophthalmology. ,vol. 12, pp. 257- 262 ,(1992) , 10.3109/01658109209058148
H A Quigley, A Hendrickson, L Dandona, Selective effects of experimental glaucoma on axonal transport by retinal ganglion cells to the dorsal lateral geniculate nucleus Investigative Ophthalmology & Visual Science. ,vol. 32, pp. 1593- 1599 ,(1991)
M O Gordon, C Kilo, W M Hart, S E Silverman, The dyschromatopsia of optic neuritis is determined in part by the foveal/perifoveal distribution of visual field damage. Investigative Ophthalmology & Visual Science. ,vol. 31, pp. 1895- 1902 ,(1990)
M Prost, F Grehn, Function of retinal nerve fibers depends on perfusion pressure: neurophysiologic investigations during acute intraocular pressure elevation. Investigative Ophthalmology & Visual Science. ,vol. 24, pp. 347- 353 ,(1983)
P Hnik, F S Mikelberg, S M Drance, N V Swindale, S L Graham, G R Douglas, B C Chauhan, Comparison of psychophysical and electrophysiological testing in early glaucoma. Investigative Ophthalmology & Visual Science. ,vol. 37, pp. 2651- 2662 ,(1996)
Yifeng Zhou, Tiande Shou, Y cells in the cat retina are more tolerant than X cells to brief elevation of IOP. Investigative Ophthalmology & Visual Science. ,vol. 30, pp. 2093- 2098 ,(1989)
Thomas David Duane, William Tasman, Duane's Clinical Ophthalmology ,(1993)