Latest Developments in Metalloenzyme Design and Repurposing
作者： Tillmann Heinisch , Thomas R. Ward
关键词:
摘要: In the past decade, artificial metalloenzymes (AMEs) have emerged as attractive alternatives to more traditional homogeneous catalysts and enzymes. This microreview presents a selection of recent achievements in design such hybrid catalysts. These include zinc hydrolases metathesases, heme-protein repurposing for C–H, N–H, S–H insertion reactions, novel light-driven redox catalysts, scaffold proteins, metallocofactor anchoring techniques metalloenzyme models.
core.ac.uk
sci-hub.se 参考文章(85)
Jay R. Winkler, Harry B. Gray, Electron flow through metalloproteins. Chemical Reviews. ,vol. 114, pp. 3369- 3380 ,(2014) , 10.1021/CR4004715
Yohei Sano, Akira Onoda, Rie Sakurai, Hiroaki Kitagishi, Takashi Hayashi, Preparation and reactivity of a tetranuclear Fe(II) core in the metallothionein α-domain. Journal of Inorganic Biochemistry. ,vol. 105, pp. 702- 708 ,(2011) , 10.1016/J.JINORGBIO.2011.01.011
Pedro S Coelho, Z Jane Wang, Maraia E Ener, Stefanie A Baril, Arvind Kannan, Frances H Arnold, Eric M Brustad, A Serine-Substituted P450 Catalyzes Highly Efficient Carbene Transfer to Olefins In Vivo Nature Chemical Biology. ,vol. 9, pp. 485- 487 ,(2013) , 10.1038/NCHEMBIO.1278
Lauren E. Roth, F. Akif Tezcan, Light‐Driven Uncoupling of Nitrogenase Catalysis from ATP Hydrolysis Chemcatchem. ,vol. 3, pp. 1549- 1555 ,(2011) , 10.1002/CCTC.201100216
Howard L. Levine, E. T. Kaiser, Oxidation of dihydronicotinamides by flavopapain Journal of the American Chemical Society. ,vol. 100, pp. 7670- 7677 ,(1978) , 10.1021/JA00492A040
Todd K. Hyster, Christopher C. Farwell, Andrew R. Buller, John A. McIntosh, Frances H. Arnold, Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination Journal of the American Chemical Society. ,vol. 136, pp. 15505- 15508 ,(2014) , 10.1021/JA509308V
Ngoc-Han Tran, Daniel Nguyen, Sudharsan Dwaraknath, Sruthi Mahadevan, Garrett Chavez, Angelina Nguyen, Thanh Dao, Sarah Mullen, Thien-Anh Nguyen, Lionel E. Cheruzel, An efficient light-driven P450 BM3 biocatalyst. Journal of the American Chemical Society. ,vol. 135, pp. 14484- 14487 ,(2013) , 10.1021/JA409337V
Woon Ju Song, F. Akif Tezcan, A designed supramolecular protein assembly with in vivo enzymatic activity Science. ,vol. 346, pp. 1525- 1528 ,(2014) , 10.1126/SCIENCE.1259680
Fabien W. Monnard, Elisa S. Nogueira, Tillmann Heinisch, Tilman Schirmer, Thomas R. Ward, Human Carbonic Anhydrase II as Host Protein for the Creation of Artificial Metalloenzymes : the Asymmetric Transfer Hydrogenation of Imines Chemical Science. ,vol. 4, pp. 3269- 3274 ,(2013) , 10.1039/C3SC51065D
Akira Onoda, Takashi Hayashi, Artificial hydrogenase: biomimetic approaches controlling active molecular catalysts. Current Opinion in Chemical Biology. ,vol. 25, pp. 133- 140 ,(2015) , 10.1016/J.CBPA.2014.12.041