Prenatal analysis of rhesus CcDEe blood groups by heteroduplex generator
作者： Nancy C. Rose , Carlyn Hurwitz , Leslie Silberstein , Rao Andovalu , Jay Stoerker
DOI: 10.1016/S0002-9378(97)70406-X
关键词:
摘要: Abstract OBJECTIVE: Our purpose was to determine the efficacy of heteroduplex generator in prenatal analysis rhesus CcDEe blood groups. STUDY DESIGN: A cross-sectional study performed evaluating fetal samples from 85 women undergoing diagnosis and comparing results with standard immunologic serotyping on cord delivery. RESULTS: Of samples, 64 were tested for all alleles; one case discrepant. Twenty-one cases solely D antigen. Two novel genotypes detected population by confirmed deoxyribonucleic acid sequencing. Five indeterminate because an indistinct banding pattern. CONCLUSIONS: Heteroduplex can identify group alleles is inexpensive, rapid, does not use radioactive isotopes. (Am J Obstet Gynecol 1997;176:1084-9.)
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