Rgma fragment based diagnostic assay

作者: Andreas Striebinger , Bernhard Klaus Mueller , Stefan Barghorn , Martin Schmidt

DOI:

关键词:

摘要: Provided are diagnostic assays and method s of using the for detecting quantifying RGMa fragments in a sample. The methods may be used detection to monitoring drug treatment effectiveness neurodegenerative diseases.

参考文章(8)
Bernhard K. Mueller, Philip Bardwell, Mary Leddy, Martin Schmidt, Eve Barlow, Chung-Ming Hsieh, Antibodies against the rgm a protein and uses thereof ,(2009)
John Memmott, Bernhard Mueller, Lili Huang, Philip D. Bardwell, Yuliya Kutskova, Composition and method for the diagnosis and treatment of diseases associated with neurite degeneration ,(2013)
Rieko Muramatsu, Takekazu Kubo, Masahiro Mori, Yuka Nakamura, Yuki Fujita, Tsugio Akutsu, Tatsusada Okuno, Junko Taniguchi, Atsushi Kumanogoh, Mari Yoshida, Hideki Mochizuki, Satoshi Kuwabara, Toshihide Yamashita, RGMa modulates T cell responses and is involved in autoimmune encephalomyelitis Nature Medicine. ,vol. 17, pp. 488- 494 ,(2011) , 10.1038/NM.2321
Nardos G. Tassew, Jason Charish, Nabil G. Seidah, Philippe P. Monnier, SKI-1 and Furin Generate Multiple RGMa Fragments that Regulate Axonal Growth Developmental Cell. ,vol. 22, pp. 391- 402 ,(2012) , 10.1016/J.DEVCEL.2011.11.022
Katsuhiko Hata, Masashi Fujitani, Yuichi Yasuda, Hideo Doya, Tomoko Saito, Satoru Yamagishi, Bernhard K. Mueller, Toshihide Yamashita, RGMa inhibition promotes axonal growth and recovery after spinal cord injury Journal of Cell Biology. ,vol. 173, pp. 47- 58 ,(2006) , 10.1083/JCB.200508143
Paolo Macchi, Bernhard K. Mueller, Bernd Stahl, Philippe P. Monnier, Friedrich Bonhoeffer, Jens S. Anderson, Matthias Mann, Use of rgm and its modulators ,(2001)