New prognostic markers in neuroblastoma

摘要: Introduction: The hallmark of neuroblastoma is its clinical and biological heterogeneity, with the likelihood cure varying widely according to age at diagnosis, extent disease tumor biology. We hope this review will be useful for understanding part unfamiliar codex. Areas covered: In first review, authors summarize currently used prognostic factors risk-adapted therapy, focus on management patients. second part, discuss evolving future treatment schemes. A search online medical research databases was undertaken focusing especially literature published in last six years. Expert opinion: Harnessing synergy various forms data, including variables biomarker profiles, would allow mathematical predictive models built individual patient, which could eventually become molecular targets specific therapies.