The Immune System: Our Body’s Homeland Security Against Disease

作者: Aristo Vojdani , Elroy Vojdani , Charlene Vojdani

DOI: 10.1007/978-3-030-30730-1_19

关键词:

摘要: The immune system acts as our body’s own homeland security department, working nonstop to identify harmful invaders and prevent them from wreaking havoc on us. It is extremely complex, compared such other vital systems the circulatory pulmonary systems. heart has one main function, while lungs have three; system, hand, performs hundreds of tasks that are divided between its two components: mucosal system. Both these subsystems themselves arms: innate arm adaptive arm. first line defense because it comes into contact with external environment triggers. Secretory IgA plays a large part in maintaining immunological tolerance providing protection for Innate or nonspecific immunity “first responder”; doesn’t need be activated by specific antigen but uses specialized cells attack destroy anything recognize “self.” Adaptive “backup team” takes longer arrive; must triggered antigens produces antibodies antigens. Essential successful functioning whole establishment tolerance, which central peripheral oral tolerance. If this mechanism disrupted environmental triggers, may start attacking healthy cells, resulting inflammation autoimmunity. Fortunately, clinicians can use protocols, including dietary interventions, keep smoothly.

参考文章(85)
Marc Veldhoen, Verena Brucklacher-Waldert, Dietary influences on intestinal immunity Nature Reviews Immunology. ,vol. 12, pp. 696- 708 ,(2012) , 10.1038/NRI3299
V Hakeem, R Fifield, H F al-Bayaty, M J Aldred, D M Walker, J Williams, H R Jenkins, Salivary IgA antigliadin antibody as a marker for coeliac disease. Archives of Disease in Childhood. ,vol. 67, pp. 724- 727 ,(1992) , 10.1136/ADC.67.6.724
Stephanie K. Lathrop, Seth M. Bloom, Sindhuja M. Rao, Katherine Nutsch, Chan-Wang Lio, Nicole Santacruz, Daniel A. Peterson, Thaddeus S. Stappenbeck, Chyi-Song Hsieh, Peripheral education of the immune system by colonic commensal microbiota Nature. ,vol. 478, pp. 250- 254 ,(2011) , 10.1038/NATURE10434
Aristo Vojdani, Igal Tarash, Cross-Reaction between Gliadin and Different Food and Tissue Antigens Food and Nutrition Sciences. ,vol. 4, pp. 20- 32 ,(2013) , 10.4236/FNS.2013.41005
J Tian, M A Atkinson, M Clare-Salzler, A Herschenfeld, T Forsthuber, P V Lehmann, D L Kaufman, Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes. Journal of Experimental Medicine. ,vol. 183, pp. 1561- 1567 ,(1996) , 10.1084/JEM.183.4.1561
Martin Mempel, Jürgen Rakoski, Johannes Ring, Markus Ollert, Severe anaphylaxis to kiwi fruit: Immunologic changes related to successful sublingual allergen immunotherapy Journal of Allergy and Clinical Immunology. ,vol. 111, pp. 1406- 1409 ,(2003) , 10.1067/MAI.2003.1497
Andrew J. Macpherson, Markus B. Geuking, Kathy D. McCoy, Homeland Security: IgA immunity at the frontiers of the body Trends in Immunology. ,vol. 33, pp. 160- 167 ,(2012) , 10.1016/J.IT.2012.02.002
Aristo Vojdani, Jonathan Erde, Regulatory T Cells, a Potent Immunoregulatory Target for CAM Researchers: Modulating Allergic and Infectious Disease Pathology (II). Evidence-based Complementary and Alternative Medicine. ,vol. 3, pp. 209- 215 ,(2006) , 10.1093/ECAM/NEL020
M. BONAMICO, R. NENNA, R. P. L. LUPARIA, C. PERRICONE, M. MONTUORI, F. LUCANTONI, A. CASTRONOVO, S. MURA, A. TURCHETTI, P. STRAPPINI, C. TIBERTI, Radioimmunological detection of anti-transglutaminase autoantibodies in human saliva: a useful test to monitor coeliac disease follow-up Alimentary Pharmacology & Therapeutics. ,vol. 28, pp. 364- 370 ,(2008) , 10.1111/J.1365-2036.2008.03720.X
Zahava Vadasz, Tharwat Haj, Aharon Kessel, Elias Toubi, B‐regulatory cells in autoimmunity and immune mediated inflammation FEBS Letters. ,vol. 587, pp. 2074- 2078 ,(2013) , 10.1016/J.FEBSLET.2013.05.023