Advances in male contraception.

摘要: Despite significant advances in contraceptive options for women over the last 50 yr, world population continues to grow rapidly. Scientists and activists alike point devastating environmental impacts that pressures have caused, including global warming from developed hunger disease less areas. Moreover, almost half of all pregnancies are still unwanted or unplanned. Clearly, there is a need expanded, reversible, options. Multicultural surveys demonstrate willingness men participate contraception their female partners trust them do so. Notwithstanding paucity options, male methods vasectomy condoms account one third use United States other countries. Recent international clinical research efforts demonstrated high efficacy rates (90–95%) hormonally based contraceptives. Current barriers expanded include limited delivery perceived regulatory obstacles, which stymie introduction marketplace. However, oral injectable androgen cause optimism these hurdles may be overcome. Nonhormonal methods, such as compounds target sperm motility, attractive theoretical promise specificity reproductive tract. Gene protein array technologies continue identify potential targets this approach. Such nonhormonal agents will likely reach trials near future. Great strides been made understanding physiology; combined scientists, clinicians, industry governmental funding agencies could make an effective, option family planning next decade.