Changes in the location and type of gastric adenocarcinoma

摘要: To document our impression of major changes in aspects gastric adenocarcinoma, we reviewed and compared 62 consecutive cases from 1975 through 1978 31 1938 1942. The average age at diagnosis increased 58 to 68 years, the male female ratio decreased approximately 1:1, carcinomas composed predominantly (50% or more) signet-ring cells (SRC) 9 39% total cases. In recent series, with SRC (compared those without SRC) occurred nine years earlier, were more frequent women, located distally, had an infiltrative growth pattern. Carcinomas originating proximal stomach (cardia) not noted old series but formed 27% These tumors showed a predominance, contained less often, commonly associated chronic gastritis. implications these observations are discussed.