作者: Marc Verstraete , Raymond Verhaeghe
DOI: 10.1007/978-3-642-75625-2_14
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摘要: The high morbidity and mortality from critical limb ischaemia as well less severe derangement of the arterial blood supply in legs, has promoted continuing search for effective methods its prevention treatment. Although most instances atherosclerosis medium sized arteries also smaller diabetes, is underlying disorder leading to ischaemia, platelet aggregation fibrin deposition on atheromatous lesions may further reduce flow (see Chapter 3). Drugs interfering with activation platelets (antiplatelet drugs, prostanoids) coagulation factors (heparin oral anticoagulants, hirudin, defibrinogenating agents, thrombolytic drugs) will therefore be considered this overview. clinical usefulness hyperbaric oxygen, plasma expanders vasoactive drugs are briefly discussed.