Cytogenetic studies of testicular germ cell tumors: pathogenetic relevance.
作者： S. M. M. J. Castedo , J. W. Oosterhuis , B. de Jong
DOI: 10.1007/978-3-642-84485-0_10
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摘要: Testicular germ cell tumors (TGCTs) are a heterogeneous group of neoplasms (see Mostofi et al. 1987; Ulbright and Roth 1987 for recent reviews). TGCTs adults can be divided clinically morphologically into two main entities: seminomas nonseminomatous (NSGCTs) (Mostofi Sobin 1977; 1980). Seminomas composed neoplastic cells sharing many histological, immunohistochemical, ultrastructural characteristics with carcinoma in situ (CIS) the testis (Jacobsen Norgaard-Pedersen 1984). NSGCTs embryonic tissues (embryonal carcinoma, immature teratoma, mature teratoma) and/or extraembryonic (yolk sac tumor choriocarcinoma). seminoma an NSGCT component called combined according to British classification (Pugh 1976). less aggressive than as (although aggressiveness depends on histological subtype, particular presence embryonal yolk tumor,
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