Acromelanosis albo-punctata: a distinct inherited dermatosis with acral spotty dyspigmentation without systemic involvement.

摘要: We describe an otherwise healthy 7-year-old boy who developed confetti-like hypopigmented macules on the dorsal aspects of hands and feet, spreading to palms soles a few months after birth. In 1964 Siemens introduced term acromelanosis albo-punctata skin features patient has remained only reported case in literature so far strongly resembles our patient. By genetic testing we excluded mutations genes known be involved diseases with acral hypo- or hyperpigmentation. review differential diagnosis localized spotty dyspigmentation conclude that may represent distinct entity.