Neuroscience of Behavioral and Pharmacological Treatments for Addictions

作者: Marc N. Potenza , Mehmet Sofuoglu , Kathleen M. Carroll , Bruce J. Rounsaville

DOI: 10.1016/J.NEURON.2011.02.009

关键词:

摘要: Although substantial advances have been made in behavioral and pharmacological treatments for addictions, moving treatment development to the next stage may require novel ways of approaching particularly based on new findings regarding neurobiological underpinnings addictions that also assimilate incorporate relevant information from earlier approaches. In this review, we first briefly review theoretical biological models addiction then describe existing pharmacologic therapies within framework. We propose directions targets are informed by recent evidence heterogeneity contributions these disorders.

参考文章(259)
George F Koob, Eric P Zorrilla, Neurobiological mechanisms of addiction: focus on corticotropin-releasing factor. Current opinion in investigational drugs. ,vol. 11, pp. 63- 71 ,(2010)
Donnelly K, Grohman K, Fals-Stewart W, Improving treatment response of cognitively impaired veterans with neuropsychological rehabilitation. Brain and Cognition. ,vol. 60, pp. 203- ,(2006)
William R. Miller, Stephen Rollnick, Motivational interviewing: preparing people for change. Guilford Press. ,(2002)
Dependence Guideline Panel, None, Treating Tobacco Use and Dependence: 2008 Update US Department of Health and Human Services. ,(2008)
Kenneth G. Blum, David Comings, Eric E. Braverman, John R. Cull, REWARD DEFICIENCY SYNDROME American Scientist. ,vol. 84, pp. 132- 145 ,(1996)
Jonah Lehrer, Don't! The secret of self-control. New Yorker (New York, N.Y. : 1925). pp. 26- 32 ,(2009)
Christian A. Heidbreder, Amy H. Newman, Current perspectives on selective dopamine D(3) receptor antagonists as pharmacotherapeutics for addictions and related disorders. Annals of the New York Academy of Sciences. ,vol. 1187, pp. 4- 34 ,(2010) , 10.1111/J.1749-6632.2009.05149.X
Garrett E. Alexander, Michael D. Crutcher, Mahlon R. DeLong, Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions. Progress in Brain Research. ,vol. 85, pp. 119- 146 ,(1991) , 10.1016/S0079-6123(08)62678-3