Neurochemical underpinnings in bipolar disorder and epilepsy.
作者： Benedikt Amann , Heinz Grunze
DOI: 10.1111/J.1528-1167.2005.463006.X
关键词:
摘要: In this article, we discuss and highlight some of the potential neurochemical underpinnings bipolar disorder (BD) epilepsy. Some similarities are found in both disorders, such as episodic course illnesses, possible mechanism kindling, efficacy antiepileptic drugs (AEDs) treatment, all pointing to a common underlying pathophysiology. Common mechanisms at level ion channels might include antikindling calcium-antagonistic potassium outward current-modulating properties AEDs. However, future research on intracellular become decisive for better understanding between disorders.
researchgate.net 
sci-hub.se 参考文章(64)
P. C. Waldmeier, P. A. Baumann, P. Wicki, J.-J. Feldtrauer, C. Stierlin, M. Schmutz, Similar potency of carbamazepine, oxcarbazepine, and lamotrigine in inhibiting the release of glutamate and other neurotransmitters. Neurology. ,vol. 45, pp. 1907- 1913 ,(1995) , 10.1212/WNL.45.10.1907
Katherine A Lyseng-Williamson, Caroline M Perry, Aripiprazole: in acute mania associated with bipolar I disorder. CNS Drugs. ,vol. 18, pp. 367- 378 ,(2004) , 10.2165/00023210-200418060-00007
ROBERT M. POST, THOMAS W. UHDE, FRANK W. PUTNAM, JAMES C. BALLENGER, WADE H. BERRETTINI, Kindling and carbamazepine in affective illness Journal of Nervous and Mental Disease. ,vol. 170, pp. 717- 731 ,(1982) , 10.1097/00005053-198212000-00002
Hansjörg Lampe, Hans Bigalke, Carbamazepine blocks NMDA-activated currents in cultured spinal cord neurons. Neuroreport. ,vol. 1, pp. 26- 28 ,(1990) , 10.1097/00001756-199009000-00008
Jean Rataud, Florence Debarnot, Véronique Mary, Jeremy Pratt, Jean-Marie Stutzmann, Comparative study of voltage-sensitive sodium channel blockers in focal ischaemia and electric convulsions in rodents Neuroscience Letters. ,vol. 172, pp. 19- 23 ,(1994) , 10.1016/0304-3940(94)90652-1
Kiyoshi Morimoto, Hitoshi Sato, Yoshitaka Yamamoto, Takemi Watanabe, Hiroshi Suwaki, Antiepileptic Effects of Tiagabine, a Selective GABA Uptake Inhibitor, in the Rat Kindling Model of Temporal Lobe Epilepsy Epilepsia. ,vol. 38, pp. 966- 974 ,(1997) , 10.1111/J.1528-1157.1997.TB01478.X
H Depoortere, D Graham, C Faure, B Scatton, B Biton, P Granger, S Z Langer, X Vige, P Avenet, Modulation of the gamma-aminobutyric acid type A receptor by the antiepileptic drugs carbamazepine and phenytoin. Molecular Pharmacology. ,vol. 47, pp. 1189- 1196 ,(1995)
Benedikt Amann, Heinz Grunze, The evolution of antiepileptic drugs for mood stabilization and their main mechanisms of action. Expert Review of Neurotherapeutics. ,vol. 3, pp. 107- 118 ,(2003) , 10.1586/14737175.3.1.107
Heinz Grunze, Jörg von Wegerer, Robert Greene, Jörg Walden, Modulation of Calcium and Potassium Currents by Lamotrigine Neuropsychobiology. ,vol. 38, pp. 131- 138 ,(1998) , 10.1159/000026528
Robert L. Macdonald, Kevin M. Kelly, Antiepileptic Drug Mechanisms of Action Epilepsia. ,vol. 36, ,(1993) , 10.1111/J.1528-1157.1995.TB05996.X