Genetic Variation in Host Defenses and Viral Infections
作者： Eunhwa Choi , Stephen J. Chanock
关键词:
摘要: Recent advances in genomics now permit the analysis of germ-line variation and susceptibility to viral infections. So far, studies have investigated genes innate immunity, but it is clear that we must look at many pathways host defenses. While HLA, chemokines cytokine defenses been fruitful, next steps require careful assessment be analyzed because likely sets SNPs or haplotypes contribute outcomes
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Mark J. Daly, John D. Rioux, Stephen F. Schaffner, Thomas J. Hudson, Eric S. Lander, High-resolution haplotype structure in the human genome. Nature Genetics. ,vol. 29, pp. 229- 232 ,(2001) , 10.1038/NG1001-229
Peter A. Zimmerman, Alicia Buckler-White, Ghalib Alkhatib, Todd Spalding, Joseph Kubofcik, Christophe Combadiere, Drew Weissman, Oren Cohen, Andrea Rubbert, Gordon Lam, Mauro Vaccarezza, Paul E. Kennedy, V. Kumaraswami, Janis V. Giorgi, Roger Detels, Jay Hunter, Michael Chopek, Edward A. Berger, Anthony S. Fauci, Thomas B. Nutman, Philip M. Murphy, Inherited Resistance to HIV-1 Conferred by an Inactivating Mutation in CC Chemokine Receptor 5: Studies in Populations with Contrasting Clinical Phenotypes, Defined Racial Background, and Quantified Risk Molecular Medicine. ,vol. 3, pp. 23- 36 ,(1997) , 10.1007/BF03401665
Robert M. Chanock, Kenneth McIntosh, Brian R. Murphy, Robert H. Parrott, Respiratory Syncytial Virus Springer, Boston, MA. pp. 471- 489 ,(1976) , 10.1007/978-1-4613-0705-1_20
Thomas Lehr nbecher, Charles B. Foster, Shaoxian Zhu, David Venzon, Seth M. Steinberg, Kathleen Wyvill, Julia A. Metcalf, Sandra S. Cohen, Joseph Kovacs, Robert Yarchoan, Andrew Blauvelt, Stephen J. Chanock, Variant genotypes of FcγRIIIA influence the development of Kaposi's sarcoma in HIV-infected men Blood. ,vol. 95, pp. 2386- 2390 ,(2000) , 10.1182/BLOOD.V95.7.2386.007K04_2386_2390
Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Molecular Biology and Evolution. ,vol. 12, pp. 921- 927 ,(1995) , 10.1093/OXFORDJOURNALS.MOLBEV.A040269
Xiaojiang Gao, George W. Nelson, Peter Karacki, Maureen P. Martin, John Phair, Richard Kaslow, James J. Goedert, Susan Buchbinder, Keith Hoots, David Vlahov, Stephen J. O'Brien, Mary Carrington, Effect of a Single Amino Acid Change in MHC Class I Molecules on the Rate of Progression to AIDS New England Journal of Medicine. ,vol. 344, pp. 1668- 1675 ,(2001) , 10.1056/NEJM200105313442203
J Glas, H.P Török, C Simperl, A König, K Martin, F Schmidt, M Schaefer, U Schiemann, C Folwaczny, The Δ32 mutation of the chemokine-receptor 5 gene neither is correlated with chronic hepatitis C nor does it predict response to therapy with interferon-α and ribavirin Clinical Immunology. ,vol. 108, pp. 46- 50 ,(2003) , 10.1016/S1521-6616(03)00059-7
F. Cocchi, A. L. DeVico, A. Garzino-Demo, S. K. Arya, R. C. Gallo, P. Lusso, Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8+ T Cells Science. ,vol. 270, pp. 1811- 1815 ,(1995) , 10.1126/SCIENCE.270.5243.1811
David Botstein, Neil Risch, Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nature Genetics. ,vol. 33, pp. 228- 237 ,(2003) , 10.1038/NG1090
Yaoxing Huang, William A. Paxton, Steven M. Wolinsky, Avidan U. Neumann, Linqi Zhang, Tian He, Stanley Kang, Daniel Ceradini, Zhanqun Jin, Karina Yazdanbakhsh, Kevin Kunstman, Daniel Erickson, Elizabeth Dragon, Nathaniel R. Landau, John Phair, David D. Ho, Richard A. Koup, The role of a mutant CCR5 allele in HIV–1 transmission and disease progression Nature Medicine. ,vol. 2, pp. 1240- 1243 ,(1996) , 10.1038/NM1196-1240